Steelers’ Derrick Harmon Delivers Strong Message on Potential Week 3 Debut

PITTSBURGH, PA — The Pittsburgh Steelers are heading into Week 3 against the New England Patriots with a defense battered by injuries, and all eyes are on rookie defensive lineman Derrick Harmon.

Harmon, the Steelers’ first-round pick (No. 21 overall) in the 2025 NFL Draft, has yet to make his debut after suffering a knee sprain during the third preseason game on August 21. He was carted off the field that night, sparking fears of a long-term setback. Early reports, however, suggested he might only miss minimal time.

Head coach Mike Tomlin wasn’t ready to promise a return this Sunday. Speaking earlier in the week, Tomlin described Harmon as “questionable at best” for Week 3.

But Harmon himself struck a more confident tone when speaking with reporters on Friday:

“I’m ready to go when my number is called.”

That optimism has fans hopeful, but the team remains cautious given the injury history and the need to keep their prized rookie healthy long-term.

The timing of Harmon’s possible return couldn’t be more critical. On Wednesday, the Steelers placed veteran Isaiahh Loudermilk on injured reserve with a high-ankle sprain, ruling him out for at least four games. Loudermilk had been filling in for Harmon during the first two weeks of the season.

With Loudermilk sidelined, the team elevated DeMarvin Leal, a third-round pick who has struggled to meet expectations, from the practice squad to the active roster. Meanwhile, veteran Dean Lowry is also on injured reserve, leaving Pittsburgh dangerously thin up front.

It’s clear the Steelers’ defensive line could use a lift. Through two weeks, the absence of Harmon’s size, power, and versatility has been noticeable. His return would not only stabilize the unit but also inject much-needed energy into a defense already stretched thin by injuries.

Whether Harmon makes his NFL debut this Sunday or has to wait a little longer, one thing is clear: the Steelers drafted him to be a difference-maker, and his time is coming soon.