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How to Watch 49ers vs. Saints in Week 2 (NFL Week 2)

Sep 12, 2025

The San Francisco 49ers and New Orleans Saints are set to clash in a compelling Week 2 showdown, and here’s everything you need to know heading into Sunday.

📺 Streaming Options

  • FUBO – top recommendation (free trial available, strong option for NFL streaming)

  • NFL+ – live games on mobile, tablet, and connected TV via NFL.com

  • Peacock – may simulcast FOX coverage in certain regions

  • Other Platforms: ESPN+, YouTube TV, DAZN (for international viewers)

  • Note for Vietnam: A VPN may be required to access FUBO or DAZN. Without official broadcast rights, international or unofficial streams could be the only option.

    💰 Betting Odds (via BetMGM Sportsbook)

    • Spread: 49ers -6.5 (must win by 7 or more points to cover)

  • Moneyline: 49ers -275 (bet $275 to win $100), Saints +220 (bet $100 to win $220)

  • Over/Under: 46.5 total points

  • 🔮 Predictions

    Sources: The Athletic, Covers.com, Dimers

    • Dimers projects a 68% chance of a 49ers win, with a predicted score: 49ers 27, Saints 20.

  • San Francisco has the advantage of a deep roster, fresh off their Week 1 victory, and an MVP-caliber performance from Brock Purdy, who threw for 298 yards and 3 touchdowns.

  • The Saints will look to rebound after their offense sputtered in Week 1, with Derek Carr completing under 55% of his passes and struggling under pressure.

  • Fan Sentiment (X, @49ersFaithful, Sept. 9, 2025):
    “Purdy, Deebo, and CMC will light up the Dome. Saints’ defense better pray for turnovers.”

    📊 Week 1 Results (2025)

    • 49ers: Defeated Chicago Bears 31–17, with RB Christian McCaffrey rushing for 112 yards and a touchdown.

  • Saints: Fell to Tampa Bay Buccaneers 24–13, as their offense converted only 4-of-13 third downs.

  • 🏟️ Game Information

    • Matchup: San Francisco 49ers vs. New Orleans Saints

  • Date/Time: Sunday, September 14, 2025 – 4:25 PM ET (3:25 PM CT, 3:25 AM Monday, Sept. 15 in Vietnam)

  • Venue: Caesars Superdome, New Orleans, Louisiana

  • TV Broadcast: FOX (U.S.)

  • 📈 Analysis

    The 49ers enter Week 2 looking like one of the NFL’s most complete teams. Their defensive line, anchored by Nick Bosa, dominated in Week 1, and the addition of veteran safety Justin Simmons has further stabilized their secondary. On offense, Brock Purdy’s chemistry with Brandon Aiyuk and George Kittle gives Kyle Shanahan’s attack plenty of balance.

    For the Saints, the path to an upset runs through rookie sensation Chris Olave Jr. and a rejuvenated run game led by Alvin Kamara. However, unless Derek Carr finds rhythm against San Francisco’s pass rush, New Orleans may struggle to keep pace.

    Chiefs Locker Room Erupts, Chris Jones Under Investigation for NFL Sports Betting in Jaguars Game - HC Andy Reid Hands Down Harsh Punishment
    Kansas City, MO – The Kansas City Chiefs' locker room is in turmoil following an NFL investigation into defensive star Chris Jones over allegations related to sports betting. Jones, a multiple-time Pro Bowler, has been placed on non-disciplinary paid leave through Week 10, while head coach (HC) Andy Reid has imposed internal penalties after a suspicious performance in the loss to the Jacksonville Jaguars. SOURCE: https://x.com/TheNFLDrop/status/1975574483990909165 The incident stems from a decisive play at the end of the game, where Jones – the Chiefs' top defensive tackle – appeared to "do absolutely nothing" to stop quarterback Trevor Lawrence from scoring the game-winning touchdown. According to sources, this lack of effort prompted the NFL to launch an investigation, suspecting possible involvement in betting, a serious violation of league rules. "He just stood there watching Lawrence run into the end zone like he was watching a movie," an anonymous teammate shared, reflecting the outrage in the locker room. Jones, 31, has been a cornerstone for the Chiefs since being selected in the second round of the 2016 NFL Draft from Mississippi State. With an impressive career including 3 Pro Bowls, 2 Super Bowl wins, and 75.5 sacks, he signed a 5-year, $158 million contract in 2023. However, this season, Jones has only recorded 2 sacks through 5 games, and his performance against the Jaguars has drawn sharp criticism from Chiefs fans on social media. HC Andy Reid reacted strongly, penalizing Jones by sidelining him from practices and requiring an internal explanation. "We do not tolerate any behavior that harms the team or undermines the integrity of the game," Reid stated post-game. "Our organization prides itself on discipline and trust, and while we await the results of the NFL's investigation, we'll handle this internally to ensure it doesn't distract from our goals. Chris is a talented player, but no one is above the standards we set here in Kansas City." Meanwhile, the Chiefs' locker room is described as "explosive" with arguments, as some players like Patrick Mahomes express disappointment but still offer support for their teammate. The NFL investigation is expected to continue, and if violations are proven, Jones could face a long-term suspension. The Chiefs, currently at 2-3, must quickly stabilize their roster ahead of their next matchup. Fans are watching closely, with many calling this potentially the "biggest scandal of the season."