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How to Watch 49ers vs. Saints in Week 2 (NFL Week 2)

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Sep 12, 2025

The San Francisco 49ers and New Orleans Saints are set to clash in a compelling Week 2 showdown, and here’s everything you need to know heading into Sunday.
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📺 Streaming Options

  • FUBO – top recommendation (free trial available, strong option for NFL streaming)

  • NFL+ – live games on mobile, tablet, and connected TV via NFL.com

  • Peacock – may simulcast FOX coverage in certain regions

  • Other Platforms: ESPN+, YouTube TV, DAZN (for international viewers)

  • Note for Vietnam: A VPN may be required to access FUBO or DAZN. Without official broadcast rights, international or unofficial streams could be the only option.

    💰 Betting Odds (via BetMGM Sportsbook)

    • Spread: 49ers -6.5 (must win by 7 or more points to cover)

  • Moneyline: 49ers -275 (bet $275 to win $100), Saints +220 (bet $100 to win $220)

  • Over/Under: 46.5 total points

  • 🔮 Predictions

    Sources: The Athletic, Covers.com, Dimers

    • Dimers projects a 68% chance of a 49ers win, with a predicted score: 49ers 27, Saints 20.

  • San Francisco has the advantage of a deep roster, fresh off their Week 1 victory, and an MVP-caliber performance from Brock Purdy, who threw for 298 yards and 3 touchdowns.

  • The Saints will look to rebound after their offense sputtered in Week 1, with Derek Carr completing under 55% of his passes and struggling under pressure.

  • Fan Sentiment (X, @49ersFaithful, Sept. 9, 2025):
    “Purdy, Deebo, and CMC will light up the Dome. Saints’ defense better pray for turnovers.”

    📊 Week 1 Results (2025)

    • 49ers: Defeated Chicago Bears 31–17, with RB Christian McCaffrey rushing for 112 yards and a touchdown.

  • Saints: Fell to Tampa Bay Buccaneers 24–13, as their offense converted only 4-of-13 third downs.

  • 🏟️ Game Information

    • Matchup: San Francisco 49ers vs. New Orleans Saints

  • Date/Time: Sunday, September 14, 2025 – 4:25 PM ET (3:25 PM CT, 3:25 AM Monday, Sept. 15 in Vietnam)

  • Venue: Caesars Superdome, New Orleans, Louisiana

  • TV Broadcast: FOX (U.S.)

  • 📈 Analysis

    The 49ers enter Week 2 looking like one of the NFL’s most complete teams. Their defensive line, anchored by Nick Bosa, dominated in Week 1, and the addition of veteran safety Justin Simmons has further stabilized their secondary. On offense, Brock Purdy’s chemistry with Brandon Aiyuk and George Kittle gives Kyle Shanahan’s attack plenty of balance.

    For the Saints, the path to an upset runs through rookie sensation Chris Olave Jr. and a rejuvenated run game led by Alvin Kamara. However, unless Derek Carr finds rhythm against San Francisco’s pass rush, New Orleans may struggle to keep pace.

    Vikings Rookie Cut Before Season Retires to Join Military Service
    The NFL is often described as the pinnacle of athletic dreams, but for one Minnesota rookie, the path to greatness has taken a turn away from the gridiron and toward a higher calling. After signing as an undrafted free agent in May, the young cornerback fought through training camp and preseason battles, hoping to carve out a roster spot on a Vikings team searching for secondary depth and identity. That player is Zemaiah Vaughn, a standout from the University of Utah who built his name as a long, competitive boundary corner with special-teams upside. Waived in late August, Vaughn stunned teammates and fans by announcing his retirement from professional football and his decision to enlist in the U.S. military, trading a Vikings jersey for a soldier’s uniform. “I lived my NFL dream in Minnesota, but being cut before the season opened another path,” Vaughn said in a statement. “This isn’t the end — it’s a higher calling. Now, I choose to serve my country with the same heart I gave the Vikings.” At 6’3” and 187 pounds, Vaughn brought elite length for a boundary role and made his mark with poise, vision, and leadership. His preseason PFF grade of 65 reflected consistency, though the roster competition proved overwhelming. For the Vikings, the move closes the chapter on a developmental project. For Vaughn, it begins a profound new journey that echoes his reputation as a “hidden gem” — a player who always found ways to rise above. Fans in Minnesota and across the college football community saluted the decision on social media, calling it “the ultimate sacrifice” and “proof that heart is bigger than the game.” Vaughn leaves the NFL, but his next mission may prove even greater.