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Buffalo Bills Face New Test of Team Loyalty as Key Receiver Goes Down with Ankle Injury

Training camp adversity continues for the Buffalo Bills as wide receiver Khalil Shakir, one of the team’s most promising young playmakers, has been sidelined indefinitely with a high-ankle sprain. The injury, suffered during Friday’s Red and Blue practice, was confirmed by head coach Sean McDermott, who described Shakir’s status as “week-to-week” moving forward.

Khalil Shakir prefers reliability over style as Buffalo Bills top receiver  | ktvb.com

Shakir, entering his fourth year, is no stranger to this setback—having battled a similar high-ankle sprain last season. This latest injury puts his return in question, though optimism remains he’ll be ready for the season opener against the Baltimore Ravens.

Fantasy Football 2025: WR Khalil Shakir player profile

Losing Shakir, a receiver who’s become a key target for Josh Allen, is a blow to the Bills’ offense and chemistry. But in classic Buffalo fashion, the team is responding with a “next man up” mentality—an approach deeply woven into the city’s pop culture and sports identity.

Khalil Shakir 2024 Player Profile | Reception Perception

“This team always rallies around each other,” coach McDermott said. “We know Khalil will attack his rehab with the same loyalty and commitment he brings to the field. In the meantime, it’s a chance for other guys to step up and show what it means to be a Buffalo Bill.”

Bills WR Khalil Shakir, DT Austin Johnson and safety Taylor Rapp ruled out  against Texans

Shakir’s injury opens up opportunities for depth receivers to compete for a bigger role and prove their own loyalty to the team, reinforcing the blue-collar, underdog ethos that defines Buffalo’s connection to its beloved Bills.

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TIME CHANGE: How to Watch 49ERS vs BUCCANEERS in Week 6 - TV, Streaming, Kickoff Info
We are announcing a change in the schedule for the San Francisco 49ers vs. Tampa Bay Buccaneers game in Week 6 of the 2025 NFL season. This game has been flexed by the NFL to optimize the broadcast schedule, ensuring the best experience for fans across the United States and internationally. Reason for the Change Optimized Broadcast Schedule: The NFL has moved this game to a primetime slot to attract a larger audience on national television networks. Team Performance: With both teams boasting an impressive 4-1 record after five weeks, this matchup is considered one of the week's most exciting, deserving a high-viewership time slot. Original schedule (before the flex) Kickoff: 1:00 PM ET (10:00 AM PT) on Sunday, October 12, 2025.  pdated schedule (after the flex) Matchup: San Francisco 49ers vs. Tampa Bay Buccaneers Time: 4:25 PM ET, Sunday, October 12, 2025 (local time in Tampa, Florida, equivalent to 1:25 PM PT) Location: Raymond James Stadium, Tampa, Florida How to Watch (U.S.) TV: CBS — Late national window (4:25 PM ET)Projected crew: Jim Nantz, Tony Romo, Tracy Wolfson Streaming: Paramount+ (with Live TV): Streams your local CBS channel (availability varies by market) YouTube TV / other vMVPDs: Watch via your local CBS affiliate (if carried) Out-of-market: NFL Sunday Ticket on YouTube/YouTube TV for Sunday afternoon out-of-market games Radio Coverage 49ers (English): Flagships (Bay Area): KNBR 680 AM and 107.7 The Bone (KSAN-FM) Also available via the 49ers Radio Network and the 49ers app/website Example local listing: 1:25 PM PT Buccaneers (English): Flagship (Tampa Bay): WXTB 97.9 FM (98 ROCK) — Gene Deckerhoff, Dave Moore, T.J. Rives SiriusXM: Channel 226 (home-team feed) Bucs Radio Network: Statewide and regional affiliates (full frequency list available via team channels) Note: Over-the-air TV/radio coverage varies by location. Share your city/county and we’ll filter the local listings for you. Betting Snapshot (as of Oct 9, 2025 — subject to change) Spread: 49ers −3.5 Over/Under: 42.5 Moneyline: 49ers −165 / Buccaneers +140Check your preferred sportsbook for the latest numbers. Stay Updated For regional broadcast maps, game-week details, and fan events, visit the official team channels and follow on social media. International viewers should confirm local carriage and blackout rules with their providers.   We look forward to your passionate support for this crucial matchup! Let’s cheer on the 49ers as they continue their journey in the 2025 season!