49ers Get Discouraging Update on Star WR Ricky Pearsall After Jaguars Loss

Santa Clara — The San Francisco 49ers had to finish their Week 4 matchup against the Jacksonville Jaguars without their promising second-year wide receiver, Ricky Pearsall. He suffered a hamstring strain in the third quarter while stretching for a deep ball and was unable to return. Initially, the training staff hoped it was a minor issue with a quick recovery, but the team ultimately ruled him out as his hamstring showed concerning tightness and swelling.

With Week 5 being their bye week, the 49ers will have extra time to assess the full extent of the injury. However, without imaging results or a specific recovery plan in place, it remains unclear whether Pearsall will be sidelined beyond the break.

The impact on the field was immediate. Pearsall has been a key factor in stretching defenses and creating space in the slot, fueling the 49ers’ explosive passing attack. Without him, San Francisco leaned heavily on Brandon Aiyuk and rookie Jauan Jennings, while also increasing the use of practice squad call-up Ronnie Bell. Although Aiyuk made a few clutch catches, gaps in route precision and contested-catch ability exposed weaknesses, particularly on third-and-long and in the red zone.

Head coach Kyle Shanahan was candid postgame:

“We saw how tough it was for Jauan Jennings to fill Ricky Pearsall’s shoes; his speed and crisp routes are irreplaceable. We thought he might shake it off and get back out there, but the latest reports are far from encouraging.”

In the short term, the coaching staff plans to ramp up play-action bootlegs on early downs, lean on short screens to protect the edges, and rely on rub/pick concepts with Aiyuk and Jennings to generate underneath separation without Pearsall’s deep threat. On the roster front, the focus remains on tactical rotations (passing vs. run support); signing a free-agent wide receiver will only be considered if medical reports indicate a prolonged recovery.

In the long term, the 49ers have a tight window to regroup before facing the Los Angeles Rams at SoFi Stadium on Friday, October 3. Despite the Rams’ preference for high tempo and blitz-heavy schemes, their secondary depth could exploit the 49ers’ depleted receiving corps. If Pearsall and Jennings remain sidelined, the burden will fall on rookies Ronnie Bell and Danny Gray, combined with pre-snap motion, to maintain offensive rhythm—but the 49ers’ dynamic attack risks being stifled. With a 3-1 record, the Rams game could be a pivotal moment in defining their season.